Bioprocess failures rarely strike without warning. They build slowly, sometimes imperceptibly. A slightly delayed nutrient feed. A subtle dip in oxygen transfer. A parameter drifting just enough to push a process off course.
Traditional monitoring tools often detect trouble only after it has become visible in critical quality attributes. By then, the batch is at risk, timelines are disrupted, and costs mount rapidly.
SimCell™ changes that equation. Designed to identify risk signals long before they escalate, SimCell empowers bioprocess teams to safeguard every run, transforming reactive problem-solving into proactive control.
Detecting Subtle Signals in Complex Systems
SimCell is powered by neuroevolution technology, allowing it to study how parameters evolve over the entire duration of a process. Rather than looking at each factor in isolation, SimCell identifies how seemingly minor variations combine to create hidden risks.
Consider a real case we encountered. A client was struggling with unexplained yield losses. Traditional data analysis showed no obvious issues. When the process data was run through SimCell, the AI discovered that small delays in glucose bolus feeds were triggering higher lactate levels later in the run. A simple adjustment to feed timing resolved the problem and prevented further yield losses.
This is not mere prediction. It is prevention.
Turning predictions into practical actions
The true value of SimCell lies in its ability to explain its findings. It does not simply flash warnings or raise red flags. Instead, it provides clear, logical reasoning for each risk it identifies and recommends practical steps teams can take to mitigate that risk.
This creates a shift in how bioprocessing teams work. Instead of waiting for deviations to appear, they can anticipate problems and implement changes before a single cell shows signs of distress.
Teams gain:
Early detection of subtle issues that could compromise a batch
Explanations of why specific conditions create risk
Concrete recommendations to adjust process parameters in time
Confidence in Every Run
Each failed batch costs money and delays product timelines. But even more damaging is the loss of confidence in a process. When teams trust their data and know they can act before issues arise, they work with greater speed and creativity.
SimCell provides this confidence. It helps teams transition from firefighting problems to building robust, reliable processes designed to perform under pressure.